Gemcitabine/Cisplatin for Resected Pancreas Cancer: Establishing the Role of ERCC1 in Treatment Decision
Stopped early · Phase 2
Conditions studied: Pancreatic Neoplasms, Pancreatic Cancer
In brief
The purpose of this study is to investigate if the investigators can use a specific marker in the pancreatic tumor itself to determine which patients will benefit from receiving combination chemotherapy of gemcitabine and cisplatin after undergoing resection of a pancreatic cancer. The investigators will also investigate if there is any benefit to receiving both chemotherapy drugs as opposed to only gemcitabine after undergoing complete resection of the tumor.
Key facts
- Study ID
- NCT01188109
- Run by
- Emory University
- People needed
- 25
- Starts
- 2010-07-01
- Expected to finish
- 2015-07-01
- Last updated by the study team
- 2016-09-28
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Adults (≥ 18 years) at the time of signing informed consent form
- Understand and voluntarily sign informed consent form
- Able to adhere to study visit schedule and other protocol requirements
- Eastern Cooperative Oncology Group (ECOG) performance status of ≤ 2
- Absolute neutrophil count ≥ 1500 / mm³
- Platelet count ≥ 100,000 / mm³
- Resectable pancreatic adenocarcinoma
- Pathologic diagnosis of pancreatic adenocarcinoma
You may not qualify if…
- Any serious medical condition, laboratory abnormality, or psychiatric illness that would prevent the subject from signing informed consent form
- A history of renal dysfunction (serum creatinine > 1.8 mg/dL)
- Presence of active infection
- Untreated second malignancy
- Pregnant or breast feeding females (A urine pregnancy test will be obtained in all women of child-bearing age at initial screening prior to study enrollment and administration of chemotherapy.)
Where it is running
- Emory University Hospital Midtown — Atlanta, Georgia, United States
- Emory University Winship Cancer Institute — Atlanta, Georgia, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.