Vitamin D for Improving Metabolic Control and Depressive Symptoms

Completed · Not applicable

Conditions studied: Depressive Symptoms, Diabetes

In brief

This study will examine whether weekly vitamin D supplementation in women with significant depressive symptoms and diabetes will exhibit improved mood and metabolic control. If supplementation with Vitamin D is beneficial, it will be a simple and cost-effective method for treatment. Women will be targeted since they have greater depression and worse metabolic control than men with diabetes.

Key facts

Study ID

NCT01185574

Run by

Loyola University

People needed

50

Starts

2009-10-01

Expected to finish

2012-05-01

Last updated by the study team

2013-07-11

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Women aged 18 and older
• medically stable type 2 diabetes with HBA1c <9%.
• significantly elevated depressive symptoms as measured by a score greater than or equal to 14 using the Center for Epidemiologic Studies Depression Tool (CES-D.

You may not qualify if…

• vitamin D levels of 32 ng/dl or greater
• malabsorption problems (e.g., crohn's disease, celiac sprue)
• hypercalcemia-level greater than 10.5 mg/dl
• Severe complications of diabetes (amputation, blindness, or renal problems) 5) Women with low thyroid function
• active suicidal ideation, a history of bipolar depression, psychotic disorders, and current alcohol or substance disorders. Active treatment for depression (e.g., antidepressant therapy) will not be exclusion criteria 7) Any serious chronic illness that may impact on their health-related quality of life and treatment effect 8) Women who are pregnant 9) Women who have had bariatric surgery.

Where it is running

• Loyola University Medical Center — Maywood, Illinois, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.