Lifestyle Modifications and the Progression of Chronic Kidney Disease

Completed · Not applicable

Conditions studied: Patients With Stage 2-4 Chronic Kidney Disease

In brief

Aerobic training has been shown to favorably alter several of the known risk factors for coronary artery disease including hypertension, dyslipidemia, obesity, and diabetes (1). It seems logical that if these risk factors were aggressively controlled in patients with chronic kidney disease (CKD) by implementing lifestyle changes (e.g., diet and exercise training) to support the pharmacologic interventions that are necessary for the control of the disease, then the rate of progression of the disease may be altered. However, to date, there is no clear research evidence to support this hypothesis. Therefore the aims of the proposed study are: 1. To test the hypothesis that lifestyle interventions (i.e., dietary modification and regular, long-term aerobic exercise training) will favorably alter the natural progression of CKD in a sample of patients compared to a control group who will receive the current standard care. 2. To explore possible mechanisms that could contribute to the observed changes.

Key facts

Study ID

NCT01179906

Run by

Springfield College

People needed

21

Starts

2006-01-01

Expected to finish

2009-02-01

Last updated by the study team

2010-08-11

Who can join

Age: 20 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Stages 2-4 CKD

You may not qualify if…

• CAD
• MI

Where it is running

• Springfield College — Springfield, Massachusetts, United States

Full record on ClinicalTrials.gov

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