Sex Differences in Attentional Bias in Marijuana-dependent Individuals

Completed · Not applicable

Conditions studied: Marijuana Dependence

In brief

The purpose of this study is to explore sex differences in cognitive functioning and responses to marijuana-related items, and to determine whether stress impacts these measures. Hypothesis 1: Attentional bias will be greater for marijuana cues in male marijuana-dependent subjects relative to female marijuana-dependent or non-dependent male controls. Hypothesis 2: Marijuana-dependent females will exhibit greater stress-induced changes in attentional bias and cognitive functioning than marijuana-dependent males.

Key facts

Study ID

NCT01179425

Run by

Medical University of South Carolina

People needed

40

Starts

2009-08-01

Expected to finish

2011-02-01

Last updated by the study team

2011-04-14

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Inclusion criteria will include subjects between the ages of 18-65 who meet full DSM-IV criteria for marijuana dependence and non-dependent controls.

You may not qualify if…

• Exclusion criteria will include medications that may affect cognitive or HPA-axis functioning
• Current depression
• Bipolar disorder
• Attention deficit hyperactivity disorder
• History of psychosis
• Suicidal or homicidal intent
• Significant cognitive deficits
• Dependence on any substance other than marijuana, nicotine, or caffeine.

Where it is running

• Medical University of South Carolina, Dept. of Psychiatry/Clinical Neuroscience Division — Charleston, South Carolina, United States

Full record on ClinicalTrials.gov

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