Esmolol Infusion During Laminectomy: Effect on Quality of Recovery
Stopped early · Phase 4 · Has a placebo group
Conditions studied: Laminectomy
In brief
The purpose of this study is to evaluate the effects of esmolol, a drug which is commonly administered during surgery to help control blood pressure and heart rate, on postoperative pain levels and requirements for pain medication.
Key facts
- Study ID
- NCT01179113
- Run by
- Cedars-Sinai Medical Center
- People needed
- 33
- Starts
- 2011-06-01
- Expected to finish
- 2015-05-01
- Last updated by the study team
- 2016-11-02
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients scheduled to undergo single-level or double-level laminectomy under general anesthesia
- Willingness and ability to sign an informed consent document
- No allergies to any of the anesthetic or analgesic medications being used for the study, as outlined in the study protocol
- Between 18-80 years of age
- American Society of Anesthesiologists (ASA) class I-III adults of either sex
You may not qualify if…
- Patients who are ASA class IV or higher
- Patients with known allergy, hypersensitivity, or contraindication to the use of any of the medications being used for the study, as outlined in the study protocol
- Patients who are heavy chronic opioid users, defined for the purposes of this study as any patient who is taking the equivalent of 10mg of oral morphine per day or greater
- Pregnant or lactating women
- Patients with a history of drug or alcohol abuse within the past 3 months
- Patients with any other medical conditions or who are using any medications which may interfere with the conduct of the study (including patients taking clonidine, patients with EKG conduction defects and who are taking calcium channel blockers, patients with clinically significant congestive heart failure (CHF) or bronchospasm, or patients with second- or third-degree heart block, symptomatic sinus bradyarrhythmia, or nonsinus rhythm on preoperative EKG.)
Where it is running
- Cedars Sinai Medical Center — Los Angeles, California, United States
Full record on ClinicalTrials.gov
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