Evaluation of Microvolt T-Wave Alternans(MTWA) Testing for the Detection of Active Ischemia

Completed

Conditions studied: Coronary Artery Disease

In brief

MTWA-CAD is a feasibility study designed to evaluate Microvolt T-Wave Alternans (MTWA) testing for the purpose of detecting active ischemia in patients with known or suspected coronary artery disease (CAD). MTWA is a subtle, alternating pattern in the T wave portion of the surface electrocardiogram (ECG) that is associated with increased risk of ventricular tachyarrhythmias and sudden cardiac arrest (SCA).

Key facts

Study ID

NCT01174797

Run by

Cambridge Heart Inc.

People needed

186

Starts

2010-06-01

Expected to finish

2013-05-01

Last updated by the study team

2013-05-27

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 18 or above, or of legal age to give informed consent specific to state and national law
• Willing and capable of providing informed consent
• Willing and capable of undergoing a SPECT MPI exercise test (or stress echo) at an approved clinical investigational center
• In normal sinus rhythm at the time of the exercise test
• A life expectancy of more than 6 months

You may not qualify if…

• In atrial fibrillation at the time of the exercise test
• Left bundle branch block (precludes ST segment measurement)
• Pacemaker-dependent
• Life expectancy of less than 6 months
• Pregnancy

Where it is running

• Connecticut Clinical Research, LLC — Bridgeport, Connecticut, United States
• Northwest Houston Heart Center — Tomball, Texas, United States

Full record on ClinicalTrials.gov

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