Idiopathic Gastroparesis Registry Using a Predominant-Symptom Classification
Stopped early
Conditions studied: Gastroparesis
In brief
The diagnosis of "gastroparesis" suggests that delayed gastric emptying is the underlying cause of symptoms, but this description fails to explain the variable presentation. There are fundamental differences in causes, symptoms, and prognosis among patients with idiopathic gastroparesis. Understanding these differences is necessary in order to provide effective treatment in these patients. We believe our classification for gastroparesis is a useful tool in the management of patients with idiopathic gastroparesis to predict clinical severity, treatment response, and future prognosis.
Key facts
- Study ID
- NCT01173484
- Run by
- University of Louisville
- People needed
- 15
- Starts
- 2010-06-01
- Expected to finish
- 2011-08-01
- Last updated by the study team
- 2017-04-10
Who can join
Age: 16 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Symptoms of gastroparesis (nausea, vomiting, bloating, dyspepsia, early satiety, or effortless regurgitation) >1 month in duration.
- Abnormal 4-hour gastric emptying scan within the past 3 months.
- Initial investigation, based on the AGA Technical Review for gastroparesis, is non-diagnostic for an underlying cause
You may not qualify if…
- Presence of endocrine or metabolic diseases: type 1 or type 2 diabetes, hypothyroidism, renal failure, adrenal insufficiency.
- Presence of post-surgical gastroparesis: gastric surgery with vagotomy (with or without gastric resection, esophagectomy; surgery without vagotomy (fundoplication, bariatric surgery, heart-lung transplant).
- Presence of neuromuscular diseases: multiple sclerosis, chronic idiopathic demyelinating polyneuropathy, myotonic dystrophy.
- Presence of connective tissue diseases: systemic sclerosis, mixed connective tissue disorder, polymyositis, dermatomyositis, lupus.
- Presence of autonomic diseases: Central (Parkinson, multiple system atrophy, Lewy body disease, brainstem disease) or Peripheral (idiopathic dysautonomia, amyloidosis, immune-mediated disease, vitamin B12 deficiency, mitochondrial disorder, porphyria, hereditary sensory autonomic neuropathy).
- Presence of paraneoplastic syndrome: small cell lung cancer, multiple myeloma, breast cancer, lymphomas, pancreatic cancer.
- Taking dopamine agonists on a daily basis.
- Presence of known viral infection (Epstein-Barr, cytomegalovirus, herpes simplex, rotavirus), Chagas disease.
- Presence of gastric outlet, small bowel or colon mechanical obstruction.
- Presence of gastric electrical stimulator.
- Non-ambulatory patients: bed-ridden, nursing home resident, etc.
- Presence of active cancer or undergoing cancer treatment.
- Less than 16 years old.
- Pregnancy.
- Unable to provide informed consent.
- Prisoners.
Where it is running
- University of Louisville — Louisville, Kentucky, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.