The Use of Near Infrared Spectroscopy in the Diagnosis of Acute Compartment Syndrome

Status unconfirmed

Conditions studied: Acute Compartment Syndrome

In brief

This is a prospective observational study to determine the reliability and accuracy of Near Infrared Spectroscopy (NIRS) to detect oxygen flow in the extremities of injured and non-injured soldiers over time. This technology may be useful in the detection of acute compartment syndrome. We hypothesize that: * NIRS values will be well-correlated with intracompartmental pressure measurements * NIRS values will be significantly different between non-injured and injured extremities, and injured extremities treated with fasciotomy for acute compartment syndrome. * NIRS values of the upper extremity and feet will correlate to values from normal legs in critical control patients and patients with unilateral sever lower extremity injuries.

Key facts

Study ID

NCT01171638

Run by

J&M Shuler

People needed

120

Starts

2011-09-01

Expected to finish

2012-12-01

Last updated by the study team

2011-06-15

Who can join

Age: 15 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• male or female subjects
• between the ages of 15 and 65 years old
• (Cohort 1 only) Admitted directly to the ICU of a participating study site
• (Cohort 2 only) Admitted to a participating study site with the following injury/mechanism combinations:
• Injuries:
• Segemental tibia shaft fracture
• Comminuted tibia shaft fracture
• Schatzker Type III-VI tibial plateau fractures
• Mechanisms:
• Fall from a height of >= 8 feet
• Motor vehicle or motorcycle crash
• Pedestrian versus automobile

You may not qualify if…

• Patients, in whom application of NIRS monitoring is viewed as an impediment to care.
• Patients with known prior leg fractures (not related to current injury)
• History of peripheral vascular disease or lower extremity vascular surgery.
• Amputation
• Diagnoses with ACS prior to enrollment
• Spinal injuries resulting in complete loss of function
• Mangled lower extremity
• Bilateral upper extremity injuries

Where it is running

• Atlanta Medical Center — Atlanta, Georgia, United States
• Grady Memorial Hospital — Atlanta, Georgia, United States

Full record on ClinicalTrials.gov

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