Myocardial Ischemia and Transfusion Pilot

Completed · Phase 3

Conditions studied: Myocardial Infarction, Unstable Angina, Coronary Artery Disease

In brief

The purpose of this study is to evaluate two approaches to red blood cell transfusion in anemic patients with acute coronary syndrome.

Key facts

Study ID

NCT01167582

Run by

Rutgers, The State University of New Jersey

People needed

110

Starts

2009-09-01

Expected to finish

2012-06-01

Last updated by the study team

2019-03-20

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• age 18 or older;
• STEMI (ST segment elevated myocardial infarction)
• NSTEMI (Non ST segment elevation myocardial infarction)
• unstable angina
• stable coronary artery disease (undergoing cardiac catheterization during the index hospitalization);
• written informed consent has been obtained
• hemoglobin concentration less than 10 g/dL at the time of random allocation.

You may not qualify if…

• bleeding cannot be controlled at the cardiac catheterization puncture site and/or require surgery to repair vessel
• retroperitoneal bleeding requiring surgery
• clinically important hemodynamic instability based on the judgment of the treating physician
• terminal malignancy or life expectancy less than 6 months
• scheduled for cardiac surgery within the next 30 days
• symptomatic at the time of randomization
• declines blood transfusion
• history of a clinically significant transfusion reaction
• inability to provide informed consent;
• enrolled in a competing study
• previous participation in the MINT trial
• any patient who in the judgment of the research team should not be enrolled in the trial. This would include, but not be limited to, factors such alcohol or drug dependence, or psychiatric illness.

Where it is running

• Brigham and Women's Hospital — Boston, Massachusetts, United States
• Robert Wood Johnson University Hospital — New Brunswick, New Jersey, United States
• Jack D. Weiler Hospital of Montefiore Medical Center — New York, New York, United States
• Montefiore Medical Center — The Bronx, New York, United States
• University of Pittsburgh Medical Center — Pittsburgh, Pennsylvania, United States
• University of Pittsburgh Data Coordinating Center — Pittsburgh, Pennsylvania, United States
• Rhode Island Hospital — Providence, Rhode Island, United States

Full record on ClinicalTrials.gov

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