Effect of Losartan in Patients With Nonobstructive Hypertrophic Cardiomyopathy

Completed · Phase 2 · Has a placebo group

Conditions studied: Hypertrophic Cardiomyopathy

In brief

The purpose of this study is to determine whether taking losartan helps people with hypertrophic nonobstructive cardiomyopathy feel better by decreasing the amount of heart muscle thickening and/or the amount of heart muscle scarring.

Key facts

Study ID

NCT01150461

Run by

Massachusetts General Hospital

People needed

20

Starts

2007-02-01

Expected to finish

2010-07-01

Last updated by the study team

2013-09-05

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients with hypertrophic cardiomyopathy
• Left ventricular outflow tract (LVOT) gradient less than 30 mm Hg at rest
• Age 18 years or older

You may not qualify if…

• Contraindication to losartan
• Already taking losartan
• Contraindication to MRI
• Hemodynamic instability

Where it is running

• Massachusetts General Hospital — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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