Effects of Amino Acids on Regional Lipid Metabolism

Completed · Not applicable · Has a placebo group

Conditions studied: Hypertriglyceridemia

In brief

Elevated fat level in blood is a risk factor for coronary heart disease, a major cause of death in America. The overall goal of this project is to test a novel treatment using nutrient (amino acid) supplementation against this condition in men and women, and to understand how this treatment works.

Key facts

Study ID

NCT01150188

Run by

University of Arkansas

People needed

125

Starts

2010-06-01

Expected to finish

2016-08-01

Last updated by the study team

2016-10-27

Who can join

Age: 50 and older, up to 75. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age 50-75 years.
• Men and Women (Women postmenopausal).
• Ability to sign informed consent, including ≥26 Mini-Mental State Exam.
• Plasma triglyceride concentration between 130-500 mg/dl.

You may not qualify if…

• Diabetes (plasma glucose: fasting ≥126 mg/dl or ≥200 mg/dl at 2 hr after 75 g glucose load).
• On diabetes medication or lipid altering agents, including over the counter fish oil/omega 3 fatty acids.
• Kidney/renal or liver disease.
• Bleeding disorders or anemia.
• Endocrine disease.
• Positive hepatitis or HIV screens.
• Alcohol abuse or drug abuse
• Score of <26 on the Mini-Mental State Exam.
• Allergy to iodine or fish products.
• Subjects with cerebral aneurysm clips, internal transistorized devices (e.g., neural stimulators), or cardiac pacemakers.

Where it is running

• University of Arkansas for Medical Science, Reynolds Aging Institute — Little Rock, Arkansas, United States

Full record on ClinicalTrials.gov

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