Effects of Perioperative Intravenous Dexamethasone on Pain in Out Patient Knee Surgery

Stopped early · Phase 4 · Has a placebo group

Conditions studied: Post Operative Pain, Nausea

In brief

The purpose of the study is to determine the opiate sparing effects of intravenously administered dexamethasone in outpatient knee surgery. Dexamethasone is a glucocorticoid with well known antiemetic effects. However, the analgesic effects of dexamethasone have not been adequately researched. Following surgery, patients are typically discharged home with PO opiates to manage post-operative pain. The investigators believe that by using VAS (Visual Analog Scale) for Pain the investigators can show that a single dose of dexamethasone can reduce pain scales and opiate consumption post-operatively, on Post Operative Day (POD 1) when compared to placebo.

Key facts

Study ID

NCT01149616

Run by

Beth Israel Deaconess Medical Center

People needed

82

Starts

2009-12-01

Expected to finish

2012-12-01

Last updated by the study team

2017-07-07

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Adult patients undergoing ambulatory knee arthroscopy surgery
• Must provide phone contact number and agree to phone followup on post operative day 1

You may not qualify if…

• Patients with major systemic disease
• Allergy or intolerance to study drug

Where it is running

• Beth Israel Deaconess Medical Center — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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