Coenzyme Q-10 and Pulmonary Arterial Hypertension

Completed · Not applicable

Conditions studied: Pulmonary Arterial Hypertension

In brief

The purpose of this study is to evaluate the effects of Coenzyme Q-10, an antioxidant, in the treatment of pulmonary hypertension.

Key facts

Study ID

NCT01148836

Run by

The Cleveland Clinic

People needed

18

Starts

2010-01-01

Expected to finish

2014-01-01

Last updated by the study team

2015-03-20

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Males and Females age equal to or greater than 18 not to exceed 65.
• Patients with PAH Class 1 (Venice 2003)
• PAH medications must not have changed for the last two months.
• Women of child-bearing age must use a double-barrier local contraception until completion of study.
• Subjects must demonstrate understanding of study and sign informed consent and have a reliable method of communication for contact and the ability to comply with the study requirements.

You may not qualify if…

• Participation in any other studies at the time of enrollment
• History of any significant illness within four weeks of starting Coenzyme Q-10
• Hepatic insufficiency (transaminase levels >4 fold the upper limit of normal or bilirubin >2 fold the upper limit of normal).
• Renal insufficiency (creatinine >2)
• Pregnancy,breast-feeding or lack of safe contraception.
• Acute heart failure
• Known allergy to the study drug or drugs similar to the study drug
• History of drug or alcohol abuse within last 12 months

Where it is running

• Cleveland Clinic — Cleveland, Ohio, United States

Full record on ClinicalTrials.gov

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