Evaluating Three Methods for Helping Syringe Exchangers Begin Methadone Maintenance
Completed · Not applicable
Conditions studied: Substance Abuse Disorder
In brief
This research is being done to evaluate the effectiveness of three different treatment strategies for helping subjects begin and adjust to methadone maintenance treatment at Addiction Treatment Services (ATS). Subjects will be randomly assigned to one of three treatment conditions: 1) Voucher-Based Stepped Care (VBSC) induction, 2) Low-threshold Stepped Care (LTSC) induction, or 3) Routine Stepped Care (RSC) induction. It is hypothesized that subjects in both the VBSC and LTSC condition will remain in treatment longer than subjects in the RSC condition. In addition, it is hypothesized that VBSC and LTSC subjects will have less drug-positive urine samples and will report less infectious disease risk behaviors than RSC subjects.
Key facts
- Study ID
- NCT01142986
- Run by
- Johns Hopkins University
- People needed
- 223
- Starts
- 2010-07-01
- Expected to finish
- 2015-10-01
- Last updated by the study team
- 2018-07-30
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Participation in the Baltimore Needle Exchange Program (BNEP)
- Expressed interest in treatment with methadone.
You may not qualify if…
- Pregnancy
- Currently in a treatment program using methadone or other agonist medications
- Failure to meet DSM-IV criteria for opioid physical dependence and CSAT guidelines for long-term use of opioid agonist medications
- Presence of an acute medical problem that requires immediate and intense medical management (e.g., AIDS defining illness; tuberculosis; unstable diabetes, hypertension, and other problems)
- Presence of a formal thought disorder, delusions, hallucinations, or imminent risk of harm to self or others (symptoms commonly associated with schizophrenia, bipolar disorder, and other major mental illnesses).
Where it is running
- Addiction Treatment Services — Baltimore, Maryland, United States
Full record on ClinicalTrials.gov
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