Efficacy and Safety Study of Abatacept Subcutaneous Plus Methotrexate in Inducing Remission in Adults With Very Early Rheumatoid Arthritis

Completed · Phase 3 · Has a placebo group

Conditions studied: Rheumatoid Arthritis

In brief

The primary purpose of the protocol is to demonstrate the ability of abatacept plus methotrexate to induce remission in patients with very early rheumatoid arthritis after 12 months of treatment and to maintain remission following 6 months of drug withdrawal.

Key facts

Study ID

NCT01142726

Run by

Bristol-Myers Squibb

People needed

511

Starts

2010-12-01

Expected to finish

2014-10-01

Last updated by the study team

2016-01-14

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• St. Joseph'S Mercy Clinic — Hot Springs, Arkansas, United States
• Sarasota Arthritis Research Center — Sarasota, Florida, United States
• Coeur D'Alene Arthrit Clin — Coeur d'Alene, Idaho, United States
• Johns Hopkins University Division Of Rheumatology — Baltimore, Maryland, United States
• Clinical Pharmacology Study Group — Worcester, Massachusetts, United States
• Arthritis Associates Of Mississippi — Jackson, Mississippi, United States
• Physician Research Collaboration, Llc — Lincoln, Nebraska, United States
• Piedmont Rheumatology, Pa — Hickory, North Carolina, United States
• Carolina Arthritis Associates — Wilmington, North Carolina, United States
• Metrohealth Medical Center — Cleveland, Ohio, United States
• Isam A. Diab, Md — Middleburg, Ohio, United States
• Alan J. Kivitz, Md, Cpi — Duncansville, Pennsylvania, United States
• Mitchell C. Feinman, Md — Orangeburg, South Carolina, United States
• Kurt Oelke, Md — Glendale, Wisconsin, United States
• Local Institution — Cairns, Queensland, Australia
• Local Institution — Maroochydore, Queensland, Australia
• Local Institution — Woodville, South Australia, Australia
• Local Institution — Heidelberg, Victoria, Australia
• Local Institution — Malvern, Victoria, Australia
• Local Institution — Victoria Park, Western Australia, Australia
• Local Institution — Brussels, Belgium
• Local Institution — Kortrijk, Belgium
• Local Institution — Merksem, Belgium
• Local Institution — Calgary, Alberta, Canada
• Rheumatology Associates Of North Alabama, P.C. — Huntsville, Alabama, United States

Full record on ClinicalTrials.gov

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