The CANTATA-D2 Trial (CANagliflozin Treatment And Trial Analysis - DPP-4 Inhibitor Second Comparator Trial)

Completed · Phase 3

Conditions studied: Diabetes Mellitus, Type 2

In brief

The purpose of this study is to evaluate the efficacy and safety of canagliflozin compared with sitagliptin in patients with type 2 diabetes mellitus who are receiving treatment with metformin and sulphonylurea and have inadequate glycemic (blood sugar) control.

Key facts

Study ID

NCT01137812

Run by

Janssen Research & Development, LLC

People needed

756

Starts

2010-07-01

Expected to finish

2012-03-01

Last updated by the study team

2015-01-15

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• All patients must have a diagnosis of T2DM and be currently treated with metformin and sulphonylurea
• Patients in the study must have a HbA1c between >=7 and <=10.5% and a fasting plasma glucose (FPG) <300 mg/dL (16.7 mmol/L)

You may not qualify if…

• History of diabetic ketoacidosis, type 1 diabetes mellitus (T1DM), pancreas or beta cell transplantation, or diabetes secondary to pancreatitis or pancreatectomy
• or a severe hypoglycemic episode within 6 months before screening

Where it is running

• Study site — Goodyear, Arizona, United States
• Study site — Mesa, Arizona, United States
• Study site — Escondido, California, United States
• Study site — Fresno, California, United States
• Study site — Greenbrae, California, United States
• Study site — La Mesa, California, United States
• Study site — Laguna Hills, California, United States
• Study site — Lancaster, California, United States
• Study site — Long Beach, California, United States
• Study site — Los Angeles, California, United States
• Study site — Norwalk, California, United States
• Study site — Pismo Beach, California, United States
• Study site — Roseville, California, United States
• Study site — Spring Valley, California, United States
• Study site — Walnut Creek, California, United States
• Study site — Watsonville, California, United States
• Study site — Denver, Colorado, United States
• Study site — Northglenn, Colorado, United States
• Study site — Milford, Connecticut, United States
• Study site — Bradenton, Florida, United States
• Study site — Cape Coral, Florida, United States
• Study site — Clearwater, Florida, United States
• Study site — Delray Beach, Florida, United States
• Study site — Miami, Florida, United States
• Study site — Mobile, Alabama, United States

Full record on ClinicalTrials.gov

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