Detecting Heart Disease Using First Pass Imaging With Gated SPECT Perfusion

Completed

Conditions studied: Ischemic Heart Disease

In brief

The aim of this study is to determine if stress first pass imaging in conjunction with a nuclear scan will improve the sensitivity for detecting heart disease. This study will also test the usefulness of a nuclear medicine camera, CDLCAM One Pass Angiography system.

Key facts

Study ID

NCT01137409

Run by

Yale University

People needed

40

Starts

2010-08-01

Last updated by the study team

2015-05-20

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Males and females age 18 through 80 years
• Female patients who are: surgically sterile (hysterectomy or bilateral tubule libation), at least one year post-menopausal, or have a negative pregnancy test on the day of treatment
• Written informed consent

You may not qualify if…

• Patient consumed food/beverage/medication containing caffeine/methylxanthines up to 12 hours prior to infusion
• Exacerbation of COPD, Asthma (actively wheezing)
• Sinus node dysfunction in absence of pacemaker
• Use of Aggrenox (ASA/Dipyridamole), Pentoxifylline (Trental) , or oral Dipyridamole (Persantine)
• Atrial fibrillation
• Pregnant/breast feeding
• Non English speaking patients
• Subject is allergic or intolerant to aminophylline, regadenoson
• Subject has a history of known or suspected bronchospastic lung disease [e.g., asthma, wheezing, chronic obstructive pulmonary disease (COPD, etc.)]
• Patients with first degree or second degree AV block

Where it is running

• Yale New Haven Hospital — New Haven, Connecticut, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.