Ventilator Settings and Comfort

Status unconfirmed · Phase 3

Conditions studied: Obesity, Chronic Obstructive Pulmonary Disease

In brief

No studies have been done to examine whether patients with obstructive lung disease and obesity are more comfortable on some ventilator settings than on others. The purpose of the current study is to examine this question systematically.

Key facts

Study ID

NCT01131390

Run by

Bridgeport Hospital

People needed

20

Starts

2010-03-01

Expected to finish

2011-12-01

Last updated by the study team

2011-06-22

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult patients (>18 y) admitted to the MICU of Bridgeport Hospital on mechanical ventilation for:
• Exacerbation of COPD (smoking history>20 pkyrs AND chest radiographic or function abnormalities supportive of the diagnosis); OR
• Body mass index>40 kg/m2 and acute on chronic hypercapnic respiratory failure.
• Patients must be awake, not have received narcotics for more than 2 hours and possess capacity to consent themselves.
• Patients must have recovered sufficiently from their acute illness to be candidates for weaning per hospital protocol i.e. not in shock, no pressors and PaO2:FiO2>120.

You may not qualify if…

• Patients extubated for comfort care only.
• Patients with successful weaning trial that otherwise clinically requires extubation.
• Patients with unresolved pneumonia, unresolved congestive heart failure, neuromuscular disease or kyphoscoliosis-related respiratory failure will also be excluded.

Where it is running

• Bridgeport Hospital — Bridgeport, Connecticut, United States (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.