Training Interventions and Genetics of Exercise Response (TIGER)

Completed

Conditions studied: Exercise Response

In brief

Obesity established in adolescence strongly predicts obesity for the remainder of adult life, and the consequences are potentially devastating, characterized by a lifelong burden of co-morbid conditions and depression. This study will provide an exposure to physical activity that is designed to teach and empower sedentary college age individuals to become physically active. The investigators will evaluate whether such exposure can result in lasting changes in exercise behavior and body composition. The study will also provide a better understanding of the genetic factors that influence persistence in an exercise program and that influence whole body response to exercise training. Altering the course of obesity in adolescence has the potential to reduce the adult prevalence of obesity and consequently attenuate the public health burden of overweight and obesity in the investigators population.

Key facts

Study ID

NCT01127919

Run by

Molly S. Bray

People needed

3773

Starts

2010-07-01

Expected to finish

2017-11-01

Last updated by the study team

2017-11-13

Who can join

Age: 18 and older, up to 30. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• 18-30 years old
• Healthy
• sedentary at baseline

You may not qualify if…

• any medical or physical contra-indication for exercise (as indicated by the subject's physician) and/or
• any known metabolic or endocrine disorder associated with alterations in body composition (e.g., lipodystrophy).
• Refusal to consent for the use of their DNA for genetic research.

Where it is running

• University of Alabama at Birmingham — Birmingham, Alabama, United States
• University of Houston — Houston, Texas, United States

Full record on ClinicalTrials.gov

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