Pilot Study Using Echocardiography to Evaluate Patients With Heart Failure and Dyssynchrony Who Have a CRT-D Device

Withdrawn before enrolling

Conditions studied: Systolic Heart Failure

In brief

Out of all the patients that receive a CRT-D ( a dual chamber pacemaker with defibrillator ) for cardiac resynchronization therapy there is approximately one-third that do not respond. We believe that by using a simple technique that includes routine echocardiography that are normally performed in these patients could help us better understand how to program their device to reach better optimization.

Key facts

Study ID

NCT01127334

Run by

University of Mississippi Medical Center

People needed

0

Starts

2010-05-01

Expected to finish

2011-05-01

Last updated by the study team

2012-04-04

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults age 18-110 years
• Must have a CRT-D (A biventricular pacemaker with defibrillator)
• Last optimization of their device (CRT-D) must not have been done in the past 3 months
• Must be optimal heart failure medical regimen. This includes target dose of beta-blocker and angiotensin converting enzyme inhibitor (ACE-I) (or equivalent; i.e angiotensin receptor blocker (ARB); or balanced preload and afterload reducers with hydralazine and nitrates.)

You may not qualify if…

• Less than 18 years of age or greater than 110 years old.
• Does not have a CRT-D
• Optimization of their device has occurred in the past 3 months
• Not on optimal medical therapy for heart failure as listed in the inclusion criteria.

Where it is running

• University of Mississippi Medical Center — Jackson, Mississippi, United States

Full record on ClinicalTrials.gov

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