Gastric pH and Anthocyanin Absorption

Completed · Not applicable · Has a placebo group

Conditions studied: Anthocyanin Metabolism

In brief

Anthocyanins are phytonutrients that provide blue, purple and red colors to fruits and vegetables. The purpose of the study is to determine whether absorption of anthocyanins occurs in the acid pH of the stomach and to determine whether altering stomach pH by use of an over-the-counter medicine, Prilosec TM, alters absorption of anthocyanins from strawberries and blackberries.

Key facts

Study ID

NCT01122160

Run by

USDA Beltsville Human Nutrition Research Center

People needed

13

Starts

2010-05-01

Expected to finish

2010-12-01

Last updated by the study team

2013-08-23

Who can join

Age: 22 and older, up to 59. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• BMI 18.5 kg/m2 to 30 kg/m2
• Age 22 to 59 years

You may not qualify if…

• Plans to have MRI analysis or other contact with MRI equipment during the study
• Has implanted or portable electro-mechanical medical device such as a cardiac pacemaker or infusion pump
• Suspected strictures, fistulas or physiological GI obstruction
• Allergy to omeprazole
• Current use of clopidogrel (Plavix) or use within the past 3 months
• Use of warfarin, prescription antifungals/anti-yeast drugs, diazepam, and digoxin
• Chronic daily use of nonsteroidal anti-inflammatory drugs (ibuprofen, naproxen, etc.)
• History of bariatric or other gastric surgery
• Frequent use of antacids
• Use of proton pump inhibitors in past 3 months
• History of acid reflux
• History of gastrointestinal disorders or gastrointestinal surgery
• History of bezoars (packed collection of partially digested or undigested material that is unable to exit the stomach)
• Crohn's disease, diverticulitis or inflammatory bowel disease
• Inability to swallow large pills
• Dysphagia (Trouble or pain with swallowing food or pills)
• Allergy to strawberries or blackberries
• Pregnant women
• Lactating women
• Pregnancy in last 12 months
• History of kidney disease
• History of liver disease
• History of metabolic disorder
• History of some cancers
• Tobacco use in past 6 months

Where it is running

• USDA's Beltsville Human Nutrition Research Center — Beltsville, Maryland, United States

Full record on ClinicalTrials.gov

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