Neural Bases of Cognitive Rehabilitation for Brain Injury
Completed · Not applicable
Conditions studied: Brain Injury
In brief
Some of the most common and disabling consequences of brain injury are deficits in cognition, such as difficulty with sustained attention, memory, organization, and goal management. The long-term goal of this research program is to develop and test novel neuroscience-based cognitive interventions for improving attentional regulation and related "executive function" brain processes involved in goal-directed behavior.
Key facts
- Study ID
- NCT01120756
- Run by
- VA Office of Research and Development
- People needed
- 35
- Starts
- 2011-10-01
- Expected to finish
- 2018-12-29
- Last updated by the study team
- 2019-08-02
Who can join
Age: 18 and older, up to 55. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Patients with a history of TBI (reported plausible mechanism of head injury, loss of consciousness with some period of post-traumatic alteration in cognition) who are > 6 months post-injury will be screened for evidence of mild-moderate residual dysfunction in executive control functions based on corroborated reports of real-world difficulties (Mayo-Portland Adaptability Inventory).
You may not qualify if…
- Severely apathetic/abulic
- aphasic
- or other reasons for patients being unable or unwilling to participate with the training tasks
- severe cognitive dysfunction
- history of neurodevelopmental abnormalities
- ongoing illicit drug or alcohol abuse (AUDIT>8)
- severe depression as measured by Beck Depression Inventory (>29)
- severe PTSD precluding participation in research activities (such as group training or MRI scanning)
- There will be no restriction in regard to gender, race and socioeconomic status.
Where it is running
- Martinez Outpatient Clinic and Community Living Center, Martinez, CA — Martinez, California, United States
Full record on ClinicalTrials.gov
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