Correlation Between Release of Cytokines From Liver Graft and Hemodynamic Instability

Completed

Conditions studied: Liver Transplantation

In brief

The primary goal of this project is to identify the source of cytokines that are released into circulation during graft reperfusion. Seventeen patients scheduled to have adult cadaveric liver transplantation at the Milton S. Hershey Medical Center were contacted as prospective participants. Blood samples were obtained from the radial artery, the portal vein, and from the graft irrigation. The level of pro-inflammatory cytokines was verified and compared with the amount of catecholamines used to maintain hemodynamic stability.

Key facts

Study ID

NCT01120743

Run by

Penn State University

People needed

17

Starts

2008-08-01

Expected to finish

2010-04-01

Last updated by the study team

2017-11-24

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• All adult patients scheduled for liver transplantation will be offered the opportunity to participate in this research.

You may not qualify if…

• Patients unable or unwilling to provide adequate informed consent will be excluded.

Where it is running

• Penn State Milton S. Hershey Medical Center, Penn State College of Medicine — Hershey, Pennsylvania, United States

Full record on ClinicalTrials.gov

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