Study of Repetitive Transcranial Magnetic Stimulation (rTMS) as Adjuvant Treatment for Depression

Stopped early · Not applicable

Conditions studied: Depression

In brief

The study will systematically investigate the use of repetitive transcranial magnetic stimulation (rTMS) in non-remitters of a selective serotonin reuptake inhibitor (SSRI) followed by a serotonin-norepinephrine reuptake inhibitor (SNRI) trial with the capacity to identify gene variants that predict rTMS response.

Key facts

Study ID

NCT01115699

Run by

Mayo Clinic

People needed

2

Starts

2010-04-01

Expected to finish

2012-03-01

Last updated by the study team

2013-12-13

Who can join

Age: 18 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Subjects whose depressive symptoms have not remitted during their participation in the "Pharmacokinetics and Pharmacodynamics of Citalopram and Escitalopram" study or the "Pharmacokinetics and Pharmacodynamics of Duloxetine" study
• Must be able to continue to take same dose of duloxetine through the course of the study

You may not qualify if…

• A history of failure for respond to Electroconvulsive Therapy (ECT)
• Any metal in the head (except in mouth)
• Implanted medication pump or cardiac pacemaker
• Have had prior brain surgery
• Have unprovoked seizure disorder or family history of treatment resistant epilepsy
• Pregnancy
• Psychiatric hospitalization within the past two weeks
• Suicide attempt with hospitalization within past three months

Where it is running

• Mayo Clinic in Rochester — Rochester, Minnesota, United States

Full record on ClinicalTrials.gov

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