Integrated Whole-Genome Analysis of Hematologic Disorders

Completed

Conditions studied: Hematologic Diseases

In brief

We will use new technologies to look at the DNA, RNA, proteins, and metabolites in the disease-containing blood, bone marrow, or tissue and normal cells from the skin. Our goal is to analyze all of the genes in the diseased and normal skin sample. By comparing the results of the diseased sample and normal skin cells and the results of the two types of genetic information (DNA and RNA), we should be able to identify genetic changes that are important for the initiation, progression, or treatment response of that particular disorder.

Key facts

Study ID

NCT01108159

Run by

Stanford University

People needed

35

Starts

2009-09-01

Expected to finish

2013-08-02

Last updated by the study team

2018-05-31

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 18 years of age or older
• Patient meets the clinical and/or pathologic criteria for the hematologic disorder being examined.
• Patient is willing to provide a skin biopsy and five 10 mL tubes of peripheral blood.

You may not qualify if…

• Less than 18 years of age
• Patient is not willing to provide a skin biopsy and five 10 mL tubes of peripheral blood.

Where it is running

• Stanford University School of Medicine — Stanford, California, United States

Full record on ClinicalTrials.gov

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