Haptoglobin Phenotype, Vitamin E and High-density Lipoprotein (HDL) Function in Type 1 Diabetes

Completed · Not applicable · Has a placebo group

Conditions studied: Type 1 Diabetes, Heart Disease

In brief

The purpose of the study is to determine whether the function of the good cholesterol (HDL cholesterol) as well as its subfractions (via NMR spectroscopy) is altered among people with type 1 diabetes and a variation in the Haptoglobin gene and to evaluate whether vitamin E supplements may improve this function.

Key facts

Study ID

NCT01098994

Run by

University of Pittsburgh

People needed

87

Starts

2010-02-01

Expected to finish

2013-12-01

Last updated by the study team

2014-06-03

Who can join

Age: 30 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Individuals with type 1 diabetes residing in the Pittsburgh, PA area (members of the Allegheny Count or Children's Hospital of Pittsburgh/Epidemiology of Diabetes Complications Registries)
• 30 years old or older
• with diabetes duration greater than 10 years or less than 10 years but with a history of heart disease

You may not qualify if…

• Allergy to vitamin E
• Stroke, MI within the past 6 months
• Unwillingness/inability to limit antioxidant supplement use to study-provided supplements

Where it is running

• University of Pittsburgh Diabetes and Lipid Research Clinic — Pittsburgh, Pennsylvania, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.