Secretin-enhanced Magnetic Resonance Cholangiopancreatography (S-MRCP) and Pancreatic Function Following Surgery
Withdrawn before enrolling · Not applicable
Conditions studied: Pancreatic Cancer
In brief
The aim of this study will be to determine whether secretin-enhanced MRCP (S-MRCP) as well as traditional magnetic resonance imaging (MRI) of the pancreas will allow the investigators to quantify the pancreas' ability to secrete hormones as well as digestive enzymes, both before and after surgery. The investigators hypothesize that S-MRCP will provide a novel non-invasive measure of pancreatic function.
Key facts
- Study ID
- NCT01094535
- Run by
- Columbia University
- People needed
- 0
- Starts
- 2007-09-01
- Expected to finish
- 2012-09-01
- Last updated by the study team
- 2015-04-06
Who can join
Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- 18 years of age and older.
- Tissue-confirmed diagnosis of pancreatic adenocarcinoma.
- Scheduled for surgical resection of the adenocarcinoma (Whipple or distal pancreatectomy).
- Able to give informed consent
You may not qualify if…
- History of any radiation therapy to the abdomen prior to surgery.
- Any contraindication to MRI, including but not limited to implanted metal devices (e.g. pacemaker, berry aneurysm clips, neural stimulator, cochlear implants, or metal in the eye).
- Treatment with an investigational drug within 1 month prior to the day of the study drug administration.
- Current enrollment in any other interventional study.
- Creatinine greater than 2.0.
- Significant liver disease, liver masses, or evidence of portal hypertension.
- Pregnancy.
- History of sensitivity to secretin.
- Unwilling or unable to sign informed consent.
Where it is running
- Columbia University Medical Center — New York, New York, United States
Full record on ClinicalTrials.gov
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