Paracervical Block for Pain Control in First Trimester Abortion

Completed · Phase 4 · Has a placebo group

Conditions studied: Legal Abortion With Complication, Pain

In brief

Many woman undergoing a surgical abortion receive a paracervical nerve block for pain reduction, in which lidocaine (a numbing medication) is injected around the cervix. These injections numb the cervix and possibly the lower part of the uterus. However, the injection can be uncomfortable and it is not well known whether it is effective in reducing pain. The purpose of this study is to determine the level of pain women experience with a surgical abortion and the effect that paracervical block might have on that pain.

Key facts

Study ID

NCT01094366

Run by

Oregon Health and Science University

People needed

121

Starts

2010-04-01

Expected to finish

2012-11-01

Last updated by the study team

2019-12-27

Who can join

Age: 18 and older, up to 60. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Age: 18 years or older
• Voluntarily requesting pregnancy termination
• Ultrasound confirmed intrauterine pregnancy up to 10 6/7 weeks gestational age
• Good general health
• English or Spanish speaking
• Be able and willing to sign an informed consent and agree to terms of the study

You may not qualify if…

• Gestational ages over 11 0/7 weeks, due to routine misoprostol use at our institutions
• Incomplete abortion
• Required or requested narcotics or IV sedation (prior to randomization)
• Patients who refuse Ibuprofen and paracervical blocks
• Contraindications or allergies to lidocaine, ibuprofen or ativan
• Significant physical or mental health condition
• Adnexal mass or tenderness on pelvic exam consistent with pelvic inflammatory disease
• Patients with known hepatic disease
• Women, who in the opinion of the investigator are not suitable for the study protocol

Where it is running

• Planned Parenthood Columbia Willamette — Portland, Oregon, United States

Full record on ClinicalTrials.gov

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