Effect of Esomeprazole 40 mg.Daily for 7 Days on Acid Reflux and Related Arousals During Sleep in Patients With GERD

Status unconfirmed · Phase 2/Phase 3

Conditions studied: Gastroesophageal Reflux Disease

In brief

The purpose of this study is to determine if esomeprazole 40 mg. once daily improves not only nighttime symptoms but also significantly reduces conscious awakenings associated with gastroesophageal reflux and consequently improves sleep quality.

Key facts

Study ID

NCT01089959

Run by

Southern Arizona VA Health Care System

People needed

20

Starts

2010-03-01

Expected to finish

2012-03-01

Last updated by the study team

2010-08-19

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Nocturnal symptoms at least twice a week.
• Ages 18-80
• Erosive esophagitis and/or abnormal pH test -
• Able to read, understand, and complete study questionnaires

You may not qualify if…

• Subjects with Barrett's esophagus or peptic stricture on endoscopy
• Subjects with normal endoscopy and pH test
• Subjects with previous upper gastrointestinal surgery

Where it is running

• Southern Arizona VA Health Care System — Tucson, Arizona, United States (enrolling)

Full record on ClinicalTrials.gov

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