Observational Study of Swallowing Function After Treatment of Advanced Laryngeal Cancer
Completed
Conditions studied: Squamous Cell Carcinoma, Laryngeal Cancer
In brief
The purpose of this prospective, multi-institutional, observational cohort study is to determine if an initial surgical approach leads to better function and quality of life than primary chemoradiation in a subset of patients with advanced hypopharyngeal and laryngeal cancers.
Key facts
- Study ID
- NCT01089803
- Run by
- University of Minnesota
- People needed
- 279
- Starts
- 2009-09-01
- Expected to finish
- 2015-08-01
- Last updated by the study team
- 2015-12-04
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Willingness and ability to complete self-administered follow-up questionnaires over the course of one year as determined by a member of the research team
- Voluntary written informed consent with the understanding that consent may be withdrawn by the patient at any time without prejudice to future medical care
- Must be at least 18 years of age
You may not qualify if…
- Require a resection that would involve more than the standard laryngectomy (total pharyngectomy, esophagectomy)
- Undergo partial laryngectomy, when open or endoscopic
- Have previously altered anatomy of the upper aerodigestive tract
- Have pre-existing dysphagia unrelated to the tumor, or neurologic disorders that could affect swallowing (Parkinson's, cerebrovascular accidents)
- Have prior malignant disease of the upper aerodigestive tract
- Have prior radiation therapy to the head and neck region
- Metastatic disease
- Unable to complete self-administered questionnaires written in simple English for cognitive, psychiatric, or other reasons that in the opinion of the enrolling investigator is likely to interfere with participation in this clinical study.
Where it is running
- Masonic Cancer Center, University of Minnesota — Minneapolis, Minnesota, United States
Full record on ClinicalTrials.gov
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