Reducing Falls With RENEW in Older Adults Who Have Fallen

Completed · Not applicable

Conditions studied: Muscle Atrophy, Physical Deconditioning

In brief

This clinical trial will compare the effects of a high intensity Resistance Exercise via Negative Work (RENEW) vs. Traditional resistance exercise (TRAD) as part of a mult-component exercise and fall-reduction program on muscle conditioning; falling risks; as well as the fall incidence in older adults who have fallen. We anticipate that muscle conditioning will mediate the effect of RENEW on falling risks and fall incidence.

Key facts

Study ID

NCT01080196

Run by

University of Utah

People needed

134

Starts

2008-04-01

Expected to finish

2014-02-01

Last updated by the study team

2022-06-21

Who can join

Age: 65 and older, up to 95. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• male or a female at least 65 years of age or older with 2 or more self-reported co-morbid conditions.
• experienced at least 1 fall (defined for this study as unintentionally coming to rest on the ground, floor, or other lower level) in the previous 12 months
• ambulatory, community dwelling with gait speed ranging from of 25m/min to 80m/min
• medically cleared by their physician to participate in a 60 minute (with rests) MCERFP
• capable of performing RENEW on the ergometer (see below)
• recall of all 3 items (or 1-2 items with a normal clock drawing test) on the Mini-Cog instrument for dementia

You may not qualify if…

• progressive diagnosed neurologic disease (e.g., Parkinson's, multiple sclerosis, Guillain-Barre, Alzheimers)
• any dystrophies or rheumatologic conditions that primarily affects muscle (muscular dystrophy, PMR)
• having already participated in a MCEFRP
• regular (3x/week) aerobic or resistance exercise performed over the past 12 months; "aerobic" defined as hiking, fast-walking, jogging, running swimming or cycling; "resistance" defined as weight training with bands, cable, free-weights or weight-machines
• Any of the following list of absolute contraindications for MRI:
• Cardiac Pacemakers (except in rare, controlled environments)
• Cochlear (inner ear) implants
• Swan-Ganz catheters with thermodilution tips
• Ferromagnetic or unidentifiable aneurysm clips of the brain
• Implanted neuro stimulators
• Metal or unidentifiable foreign bodies in the eyes
• Shrapnel near a vital organ
• Extreme claustrophobia

Where it is running

• Department of Physical Therapy, University of Utah — Salt Lake City, Utah, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.