Gastric Accommodation and Gastroesophageal Reflux

Stopped early

Conditions studied: Gastroesophageal Reflux Disease

In brief

Gastroesophageal reflux events generally happen during relaxation of lower esophageal sphincter. This relaxation is a reflex that is triggered by gastric stimuli. The investigators hypothesize that abnormal relaxation of the gastric wall after a meal may lead to reflux events. To test this hypothesis, a study was designed to measure the gastric accommodation in patients undergoing esophageal impedance monitoring.

Key facts

Study ID

NCT01078064

Run by

Nationwide Children's Hospital

People needed

10

Starts

2010-03-01

Expected to finish

2010-11-01

Last updated by the study team

2019-03-21

Who can join

Age: 1 and older, up to 30. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• children and adolescents older than 1-year old who were referred for combined esophageal impedance pH monitoring for GERD* symptoms

You may not qualify if…

• continuous feeding
• previous fundoplication

Where it is running

• Nationwide Children's Hospital — Columbus, Ohio, United States

Full record on ClinicalTrials.gov

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