Autoimmunity in Sisters of Lupus Patients

Completed

Conditions studied: Systemic Lupus Erythematosus

In brief

This study enrolled over 400 unaffected sisters of young women diagnosed with SLE. These unaffected sisters are being followed with an annual health questionnaire (CSQ) and blood sample.

Key facts

Study ID

NCT01076101

Run by

Northwell Health

People needed

817

Starts

2009-02-01

Expected to finish

2016-12-31

Last updated by the study team

2017-02-06

Who can join

Age: 10 and older, up to 45. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Proband must be a female and have documented SLE that meets ACR criteria. SLE must be diagnosed by and including age 40.
• Proband must have at least one biological sister ≥ 10 years of age and ≤ 45 who is available and willing to donate a blood sample and enroll in a longitudinal study. Both full and half siblings qualify.

You may not qualify if…

• If inclusion criteria above are met for the proband, there are no exclusions.
• Sister who does not have SLE:
• Inclusion Criteria:
• Female with a full or half sister who has been documented SLE that meets ACR criteria.
• Sister must be currently between ages ≥ 10 and ≤ 45 at the time of enrollment and not have a diagnosis of SLE.
• Sister must be able to complete questionnaires and should be willing to donate a blood sample at baseline and follow-up.
• Sister should communicate to the recruiter that she is willing to be followed for a period of at least two years by phone and/or internet.
• Exclusion Criteria:
• If Sister meets inclusion criteria, there will be no exclusions.

Where it is running

• The Feinstein Institute for Medical Research — Manhasset, New York, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.