The Effects of a Dietary Supplement on Exercise Performance in Healthy Older Adults"

Completed · Not applicable · Has a placebo group

Conditions studied: Excessive Physical Exercise, Unspecified

In brief

Human exercise capacity decreases with aging. One explanation may be that blood vessels stiffen with age and release less of a compound called nitric oxide (NO). This compound normally relaxes blood vessels and increases blood flow to muscles, but damaging compounds called free radicals can interfere with this process. Antioxidants may help prevent free radicals from inactivating nitric oxide. The purpose of this study was to investigate the effects of an antioxidant supplement that supports NO production on exercise performance in elderly male cyclists.

Key facts

Study ID: NCT01073332
Run by: University of California, Los Angeles
People needed: 16
Starts: 2004-10-01
Expected to finish: 2005-02-01
Last updated by the study team: 2015-05-08

Who can join

Age: 50 and older, up to 75. Sex: any. Healthy volunteers: accepted.

You may qualify if…

Males and females
Age 50-75 years, inclusive
Ability to perform pulmonary function and exercise tests
Willingness to take supplement powder for 3 weeks
Ethical: Subject must sign the Institutional Review Board-approved written informed consent prior to he initiation of any study specific procedures or randomization. A subject will be excluded for any condition that might compromise the ability to give truly informed consent for participation in the study.

You may not qualify if…

Existing pulmonary or cardiovascular disease
Previous cardiac surgery
Not able to tolerate breathing through mouthpiece for up to 20 minutes
Musculoskeletal disease that would limit exercise

Where it is running

University of California, Los Angeles — Los Angeles, California, United States

Full record on ClinicalTrials.gov

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