Treatment Interruption of Natalizumab

Completed · Phase 2 · Has a placebo group

Conditions studied: Relapsing Remitting Multiple Sclerosis

In brief

This is a randomized, rater blinded trial in patients who interrupt treatment with natalizumab with or without being treated with other immunomodulatory drugs, or continue treatment with natalizumab. The main purpose of this study is to find out the following, when participants stop taking natalizumab for 24 weeks: * when MS symptoms return, and * if other drugs for MS may help control MS symptoms during the natalizumab-interruption period. This study will also explore how quickly the effects of natalizumab return after resuming natalizumab dosing.

Key facts

Study ID
NCT01071083
Run by
Biogen
People needed
175
Starts
2010-03-01
Expected to finish
2011-11-01
Last updated by the study team
2013-09-19

Who can join

Age: 18 and older, up to 60. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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