Treatment Efficacy and Toxicity in Rheumatoid Arthritis Database and Repository

Completed

Conditions studied: Rheumatoid Arthritis

In brief

To stimulate collaborative efforts of federal funding agencies, voluntary health agencies, professional organizations and industry partners to enable creation of a large, sustainable database and repository to better understand the molecular basis of treatment and rapidly accelerate translational research in RA.

Key facts

Study ID

NCT01070121

Run by

University of Alabama at Birmingham

People needed

200

Starts

2010-02-01

Expected to finish

2012-08-01

Last updated by the study team

2015-10-14

Who can join

Age: 19 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 19 years or older;
• Diagnosis of RA based on the cumulative presence of at least 4 of 7 ACR Criteria;
• Willing and able to provide informed consent; and
• One of the following:
• Starting MTX OR
• Previous or current use of Methotrexate and starting (or switching to) any of the following medications (with or without MTX)
• Etanercept
• Infliximab
• Adalimumab
• Rituximab
• Abatacept
• Golimumab
• Certolizumab
• Tocilizumab
• There is no minimum disease activity (number of swollen joints, DAS28, CRP or ESR, etc.) necessary for enrollment. Treatment decisions are entirely at the discretion of the treating rheumatologist.
• There are no combinations of drugs to be excluded, except those that do not include at least one of the seven drugs noted above.
• Use of corticosteroids (oral, parenteral, intra-articular) is allowed, but must be recorded.

You may not qualify if…

• Concomitant diagnosis of RA and systemic lupus erythematosus, juvenile arthritis, psoriatic arthritis, hepatitis C infection, current pregnancy or lactation.

Where it is running

• University of Alabama at Birmingham — Birmingham, Alabama, United States
• Stanford University — Palo Alto, California, United States
• University of Colorado in Denver — Aurora, Colorado, United States
• Johns Hopkins University — Baltimore, Maryland, United States
• Brigham and Women's Hospital — Boston, Massachusetts, United States
• University of Nebraska Medical Center — Omaha, Nebraska, United States
• North Shore Medical Center (LIJ Health System) — Lake Success, New York, United States
• Duke University — Durham, North Carolina, United States
• University of Pittsburgh — Pittsburgh, Pennsylvania, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.