Fluid Lavage of Open Wounds (FLOW): Pilot Trial

Completed · Not applicable

Conditions studied: Infection, Wound Healing Problem, Nonunion

In brief

The purpose of this trial is to investigate whether irrigation solution (soap vs. saline solution), or irrigation pressure (high vs. low) will decrease the rate of infection among patients with open fracture wounds.

Key facts

Study ID

NCT01069315

Run by

McMaster University

People needed

111

Starts

2006-07-01

Expected to finish

2008-06-01

Last updated by the study team

2019-03-18

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• skeletally mature
• sustained an open fracture of the appendicular skeleton (type I to IIIb).

You may not qualify if…

• vascular deficit
• [any] allergy to detergents or castile soap
• previous wound infection or osteomyelitis
• previous fracture with retained hardware in the injured extremity
• operative management more than 24 hours after injury
• use of immunosuppressive medication within six months
• immunological deficiency or disease conditions
• fractures of the hands (distal to the carpus) or toes

Where it is running

• University of Missouri Health Care — Columbia, Missouri, United States
• Greenville Hospital System — Greenville, South Carolina, United States
• East Texas Medical Centre — Tyler, Texas, United States
• Queen Elizabeth II Health Sciences Centre — Halifax, Nova Scotia, Canada
• Hamilton Health Sciences — Hamilton, Ontario, Canada
• Ottawa Hospital - Civic Campus — Ottawa, Ontario, Canada
• St. Michael's Hospital — Toronto, Ontario, Canada
• Sunnybrook Health Sciences Centre — Toronto, Ontario, Canada
• Sancheti Institute for Orthopaedics & Rehabilitation — Pune, Maharashtra, India

Full record on ClinicalTrials.gov

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