Vitamin D Supplementation Reduces Renin-Angiotensin System Activity in Obesity

Completed · Not applicable

Conditions studied: Obesity, Vitamin D Deficiency, Hypertension

In brief

Hypothesis: Vitamin D supplementation lower renin-angiotensin system activity in obesity. Specific Aim: To investigate whether Vitamin D supplementation in obesity improves the vascular sensitivity to angiotensin II.

Key facts

Study ID

NCT01068418

Run by

Brigham and Women's Hospital

People needed

26

Starts

2010-02-01

Expected to finish

2011-09-01

Last updated by the study team

2017-03-30

Who can join

Age: 18 and older, up to 64. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• age < 65,
• Cr < 1.6,
• 25-hydroxyvitamin D < 25 ng/mL,
• BMI > 30 kg/m2,
• stage I hypertension.

You may not qualify if…

• diabetes,
• coronary heart disease,
• heart failure,
• renal failure,
• liver failure,
• hyperparathyroidism,
• granulomatous disease.

Where it is running

• Brigham and Women's Hospital — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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