Glycemic Index and Brain Function

Completed · Not applicable

Conditions studied: Obesity

In brief

The investigators propose examine the effects of the dietary factor glycemic index (GI) on brain areas that control food intake and hunger. This knowledge could help design dietary approaches that decrease hunger, and thus promote new weight loss strategies.

Key facts

Study ID

NCT01064778

Run by

Beth Israel Deaconess Medical Center

People needed

12

Starts

2010-02-01

Expected to finish

2011-09-01

Last updated by the study team

2012-02-02

Who can join

Age: 18 and older, up to 35. Sex: male. Healthy volunteers: accepted.

You may qualify if…

• Males age 18 to 35 years
• BMI less than or equal to 25 for age and gender

You may not qualify if…

• weight > 300 lbs
• largest body circumference > 144cm
• body shape incompatible with MRI scanner or equipment
• MRI exclusion criteria
• large fluctuations in body weight (5% over preceding 6 months, 2.5% during the study)
• known medical problems that may affect metabolism or hormones
• diabetes mellitus (fasting plasma glucose ≥126 mg/dL)
• other abnormal laboratory screening tests
• taking any medications or dietary supplements that might affect body weight, appetite, or energy expenditure
• smoking or illicit substance abuse
• high levels of physical activity (>30 minutes per day, > 4days per week)
• currently following a weight loss diet
• allergies or intolerance to eggs, vanilla extract, equal, canola oil, milk, cornstarch, corn syrup

Where it is running

• Children's Hospital Boston — Boston, Massachusetts, United States
• Beth Israel Deaconess Medical Center — Boston, Massachusetts, United States
• Brigham and Women's Hospital — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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