Safety Study of a Single IVT Injection of QPI-1007 in Chronic Optic Nerve Atrophy and Recent Onset NAION Patients
Completed · Phase 1
Conditions studied: Optic Atrophy, Non-arteritic Anterior Ischemic Optic Neuropathy
In brief
This is an open-label, dose escalation, safety, tolerability and pharmacokinetic study, where active study drug (QPI-1007) will be given to all patients who participate. This study will determine whether QPI-1007 is safe when it is injected into the eye. The study will also reveal if there are any side effects of the drug and how long it takes for the body to clear the drug.
Key facts
- Study ID
- NCT01064505
- Run by
- Quark Pharmaceuticals
- People needed
- 48
- Starts
- 2010-02-01
- Expected to finish
- 2013-04-01
- Last updated by the study team
- 2013-05-13
Who can join
Age: 50 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Retinal Consultants of Arizona — Phoenix, Arizona, United States
- Retina-Vitreous Associates Medical Group — Beverly Hills, California, United States
- Jules Stein Eye Institute, University of California, Los Angeles — Los Angeles, California, United States
- Rocky Mountain Multiple Sclerosis Center at Anschutz Medical Campus, University of Colorado — Aurora, Colorado, United States
- Bascom Palmer at the University of Miami — Miami, Florida, United States
- Sarasota Retina Institute — Sarasota, Florida, United States
- University of Illinois at Chicago, Eye and Ear Infirmary — Chicago, Illinois, United States
- Kansas University Medical Center — Kansas City, Kansas, United States
- University of Kentucky, Department of Ophthalmology — Lexington, Kentucky, United States
- University of Minnesota, Department of Ophthalmology — Minneapolis, Minnesota, United States
- Mason Eye Institute, University of Missouri — Columbia, Missouri, United States
- New York Eye and Ear Infirmary — New York, New York, United States
- Flaum Eye Institute, University of Rochester Medical Center — Rochester, New York, United States
- Western Carolina Retinal Associates — Asheville, North Carolina, United States
- Charlotte Eye, Ear, Nose and Throat Associates, PA — Charlotte, North Carolina, United States
- Duke Eye Center, Duke University Medical Center — Durham, North Carolina, United States
- Cole Eye Institute, Cleveland Clinic Foundation — Cleveland, Ohio, United States
- University of Pennsylvania, Department of Ophthalmology — Philadelphia, Pennsylvania, United States
- Allegheny Ophthalmic and Orbital Associates — Pittsburgh, Pennsylvania, United States
- Alkek Eye Center Baylor College of Medicine — Houston, Texas, United States
- John A. Moran Eye Center at the University of Utah — Salt Lake City, Utah, United States
- Virginia Commonwealth University — Richmond, Virginia, United States
- Soroka University Medical Center, Dept of Ophthalmology — Beersheba, Israel
- Bnai Zion Medical Center — Haifa, Israel
- Rabin Medical Center, Belinson Campus, Dept of Ophthalmology — Petah Tikva, Israel
Full record on ClinicalTrials.gov
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