Effect of Dietary Fat When Eaten With Fructose Versus Glucose

Completed · Not applicable

Conditions studied: Body Weight Changes

In brief

This study is designed to test the effects on liver fat of varying fat intake in the presence of fructose or glucose. We hypothesize that higher dietary fat when eaten with fructose as compared to glucose will increase the amount of hepatic lipid as measured by magnetic resonance spectroscopy.

Key facts

Study ID

NCT01061346

Run by

Pennington Biomedical Research Center

People needed

19

Starts

2009-10-01

Expected to finish

2015-03-01

Last updated by the study team

2016-01-25

Who can join

Age: 28 and older, up to 55. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• BMI between 25 and 35 kg/m2 inclusive
• At least one of the following:
• Impaired fasting glucose between 100-125 mg/dl inclusive
• HDL below 40 mg/dl for men or below 50 mg/dl for females
• Triglycerides between 150 mg/dl and 400 mg/dl inclusive
• Blood pressure above or equal to 135 / 85 mm Hg
• Waist circumference >94cm (37 inches) for men or >80cm for women
• Mainly Healthy

You may not qualify if…

• Unable or unlikely to eat study foods and only foods provided by PRBC
• Taking routine medications except birth control pills
• Smoke, Abuse drugs,or Alcohol
• Pregnant or breastfeeding, irregular menstrual cycles, Post-menopausal,or PCOS
• Diabetes, heart, lung, liver, blood, or Kidney disease

Where it is running

• Pennintgon Biomedical Research Center — Baton Rouge, Louisiana, United States

Full record on ClinicalTrials.gov

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