Epithelial Healing and Visual Outcomes Using Omega-3 Therapy Before and After Photorefractive Keratectomy (PRK) Surgery

Completed · Not applicable

Conditions studied: Refractive Error

In brief

The purpose of this study is to demonstrate that omega-3 supplement can be use as an adjunct therapy for PRK patients. The investigators believe that omega-3 supplement will reduce the size of persistent epithelial defects (PEDS) and eventually hasten the corneal reepithelialization after PRK surgery. If the outcome of this study proves to be effective, then PRK would be a more attractive option to those seeking refractive treatment.

Key facts

Study ID

NCT01059019

Run by

University of California, San Diego

People needed

17

Starts

2010-01-01

Expected to finish

2011-05-01

Last updated by the study team

2013-06-21

Who can join

Age: 18 and older, up to 28. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Male or female candidate for PRK with refractive error of -1.00 to -6.00
• Male or female 18- 28 (may consider increasing this range) years old and >60 years old post cataract surgery for enhancement.
• Patients without history of diabetes.
• Patients without history of hemorrhagic stroke.
• Patient without history of blood dyscrasia.
• Patient without history of diarrhea, abdominal bloating, and indigestion.
• Patient without history of peptic ulcer disease, gastroesophageal reflux and gastroesophageal reflux disease.

You may not qualify if…

• Male or female < 18 years old for PRK.
• Male or female with a refractive error < -1.00 or >-6.00
• Patient with history of diabetes.
• Patient with history of hemorrhagic stroke.
• Patient with history of Blood dyscrasia.
• Patient with history of peptic ulcer disease, gastroesophageal reflux and gastroesophageal reflux disease.
• Patient with history of diarrhea, abdominal bloating and indigestion.
• Pregnant women and women that are lactating (nursing mothers)

Where it is running

• UCSD Shiley Eye Center — La Jolla, California, United States

Full record on ClinicalTrials.gov

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