Ovarian Freezing Before Cancer Treatment

Stopped early

Conditions studied: Effects of Chemotherapy

In brief

Women of reproductive age who will undergo cancer treatment may participate in a study to surgically remove ovarian tissue and store it, frozen, for their potential use in the future. 20% of collected tissue will be used for research.

Key facts

Study ID

NCT01057745

Run by

University of Pennsylvania

People needed

31

Starts

2007-06-12

Expected to finish

2020-03-31

Last updated by the study team

2021-04-15

Who can join

Age: 18 and older, up to 42. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Female patient between the ages of 18 and 42 years.
• In need of imminent cancer treatment, including surgery, chemotherapy or radiation therapy, which is viewed as likely to result in a permanent and complete loss of subsequent ovarian function or have a health condition that will result in premature ovarian failure. These include, but are not limited to: abdominopelvic irradiation, total body irradiation, alkylating-intensive chemotherapy, and removal of ovaries as part of their cancer treatment.
• Reasonably good health.
• Two ovaries.
• Able to defer definitive cancer therapy for approximately 3 days until the patient recovers from laparoscopic oophorectomy.

You may not qualify if…

• Patients considered as high risk for surgical complications will be excluded from the research protocol.

Where it is running

• Penn Fertility Care, 3701 Market Street, Suite 800 — Philadelphia, Pennsylvania, United States

Full record on ClinicalTrials.gov

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