Bioavailability of Avenanthramide-Enriched Oats in Healthy Older Adults
Completed · Not applicable · Has a placebo group
Conditions studied: Healthy
In brief
This is a placebo-controlled, crossover study investigating the pharmacokinetic bioavailability of avenanthramides from avenanthramide-enriched oats and their in vivo metabolites in a cohort of healthy, older adults.
Key facts
- Study ID
- NCT01055717
- Run by
- Tufts University
- People needed
- 12
- Starts
- 2010-03-01
- Expected to finish
- 2011-01-01
- Last updated by the study team
- 2013-05-27
Who can join
Age: 50 and older, up to 70. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Men and postmenopausal women
- BMI 18.5-29.9 kg/m2
You may not qualify if…
- Cigarette smoking and/or nicotine replacement use
- Use of cholesterol-lowering medications
- Use of blood pressure-lowering medications
- Use of any stomach acid-lowering medications
- Cardiovascular (heart) disease
- Gastrointestinal disease
- Kidney disease
- Endocrine disease: including diabetes, untreated thyroid disease
- Rheumatoid arthritis
- Active treatment for any type of cancer, except basal cell carcinoma, within 1 year prior to study admission
- Systolic blood pressure > 150 mm Hg and/or diastolic blood pressure > 95 mm Hg
- Regular use of oral steroids
- Regular daily intake of 2 or more alcoholic drinks
- Illicit drug use
- No fish oil supplements (including cod liver oil) for one month prior to study admission
- No dietary supplements, including those containing any vitamins, minerals, herbs, plant concentrates (including garlic, gingko, St. John's wort) or homeopathic remedies, for one month prior to study admission
Where it is running
- Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University — Boston, Massachusetts, United States
Full record on ClinicalTrials.gov
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