Stimulation of Sensation and Improvement in Swallowing Using Oral Capsaicin

Completed

Conditions studied: Dysphagia, Gastroesophageal Reflux

In brief

This is a research study to learn more about whether capsaicin, a natural ingredient of chili peppers that makes them taste "hot", can improve swallowing function. The purpose of this study is to evaluate whether sucking on a capsaicin lozenge improves sensation in the throat enough to improve swallowing function.

Key facts

Study ID

NCT01053286

Run by

University of California, Davis

People needed

19

Starts

2009-10-01

Expected to finish

2012-07-01

Last updated by the study team

2017-05-30

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Patients older than 18 years of age
• Patients with the following condition: dysphagia, globus, gastroesophageal reflux, neurological disease affecting swallowing or any other condition requiring dynamic swallow study
• Patients willing to provide written informed consent for their participation in the study

You may not qualify if…

• Patients unable to complete a full dynamic swallow study protocol
• Patients enrolled in another investigational clinical trial that interferes with any testing or testing results
• Patients who are pregnant
• Patients with known sensitivities or allergies to capsaicin or peppers, or nightshades (tomato, bell pepper, eggplant) or latex
• Patients who are prisoners
• Patients who are unable to keep a capsaicin lozenge in their mouth safely for 5 minutes

Where it is running

• University of California Davis Medical Center — Sacramento, California, United States

Full record on ClinicalTrials.gov

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