Post Operative Sore Throat and Dexamethasone

Completed · Phase 4 · Has a placebo group

Conditions studied: Sore Throat, Pain

In brief

Sore throat is a common postoperative complaint that can lead to morbidity and patient dissatisfaction . The incidence of sore throat has been reported to be between 6% and 90% even under optimal intubating conditions. There are several factors that have been shown to contribute to postoperative sore throat such as patient related factors, type of anesthesia and type of surgery. Corticosteroids are also commonly used in the perioperative period to potentiate analgesics and as antiemetics. The preoperative administration of dexamethasone can decrease the incidence and severity of postoperative sore throat which is rated by patients as one of the most undesirable outcomes in the postoperative period.

Key facts

Study ID

NCT01052038

Run by

Northwestern University

People needed

120

Starts

2010-01-01

Expected to finish

2010-09-01

Last updated by the study team

2012-05-02

Who can join

Age: 18 and older, up to 64. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Female patients undergoing outpatient laparoscopic gynecologic surgery
• ASA PS I and II
• Age between 18 and 64 years
• Fluent in English

You may not qualify if…

• History of recent respiratory tract infection
• Pregnancy, breastfeeding
• Current treatment with analgesics
• Current use of corticosteroids
• Anticipated difficult intubation
• Risk factors for post-operative aspiration

Where it is running

• Northwesten University — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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