Prolonged Exposure for Post Traumatic Stress Disorder (PTSD) Among Operation Iraqi Freedom/Operation Enduring Freedom (OIF/OEF) Personnel
Completed · Not applicable
Conditions studied: Posttraumatic Stress Disorders, Combat Disorders
In brief
The purpose of this study is 1) to evaluate whether massing 10 PE sessions in 2 weeks (massed trials; M-PE) is more efficacious than Minimal Contact control (MCC); 2) whether the massed sessions format retains the efficacy of treatment compared to 10 PE sessions spaced over 8 weeks (spaced trials; S-PE), and 3) to evaluate for the first time the efficacy of the 10 PE sessions delivered in 8 weeks in an active duty population by comparing it to an active comparison condition, Present-Centered Therapy (PCT).
Key facts
- Study ID
- NCT01049516
- Run by
- University of Pennsylvania
- People needed
- 366
- Starts
- 2010-11-01
- Expected to finish
- 2018-08-01
- Last updated by the study team
- 2018-11-27
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Adult male and female active-duty OIF/OEF military personnel and recently separated OIF/OEF veterans ages 18-65 seeking treatment for PTSD
- Diagnosis of PTSD determined by a clinician-administered Posttraumatic Stress Scale (PSS-I).
You may not qualify if…
- Current bipolar disorder or other psychotic disorder (as determined by the evaluator conducting the patient interview and medical record review)
- Current alcohol dependence (as determined by the AUDIT)
- Evidence of a moderate or severe traumatic brain injury (as determined by the inability to comprehend the baseline screening questionnaires)
- Current suicidal ideation severe enough to warrant immediate attention (as determined by the Scale for Suicidal Ideation)
- Other psychiatric disorders severe enough to warrant designation as the primary disorder
Where it is running
- Center for the Treatment and Study of Anxiety, University of Pennsylvania — Philadelphia, Pennsylvania, United States
- Carl R. Darnall Army Medical Center — Killeen, Texas, United States
- University of Texas Health Science Center at San Antonio — San Antonio, Texas, United States
Full record on ClinicalTrials.gov
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