Exercise for Stable Myasthenia Gravis

Status unconfirmed · Phase 1

Conditions studied: Myasthenia Gravis

In brief

Generalized fatigue in myasthenia gravis results in physical deconditioning that reduces fitness and increases risk of obesity, hypertension, elevated cholesterol and type 2 diabetes. This study will examine how active and fit are 30 individuals with chronic, generalized myasthenic subjects. This study will also determine whether a 3 month home exercise program with aerobic, resistive, and pulmonary training can improve physical activity, strength, fitness, lung function and reduce cardiovascular disease risk.

Key facts

Study ID

NCT01047761

Run by

Baltimore VA Medical Center

People needed

30

Starts

2010-01-01

Expected to finish

2020-12-01

Last updated by the study team

2016-11-01

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• stable generalized myasthenia gravis
• adults age 18-70

You may not qualify if…

• already performing regular exercise
• unstable angina
• recent (<3 month) myocardial infarction, stroke, hospitalization for major illness or major surgery
• chronic pain or orthopedic condition restricting exercise
• active cancer, excluding basal cell cancer
• anemia (HCT <30)
• pregnancy
• myasthenia gravis exacerbation in past 3 months

Where it is running

• University of Maryland and Baltimore VA Medical Center — Baltimore, Maryland, United States (enrolling)

Full record on ClinicalTrials.gov

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