In-Vivo Bleeding Volume Test for Platelet-Aspirin Interaction

Status unconfirmed · Phase 1 · Has a placebo group

Conditions studied: Healthy

In brief

Purpose of the present research project is to study a new in-vivo test for abnormal platelet function and to study the effect of certain drugs on clinical bleeding. This is a randomized clinical trial of a new in-vivo test of platelet function known as the bleeding volume test(BVT)which relies on an on-line measurement system. This trial will assess the sensitivity and specificity of the new BVT by studying the effects of aspirin which is known to affect platelet function in-vivo. This is not a clinical trial of drugs. This is a clinical trial of a novel in-vivo on-line laboratory test. The BVT measures the total volume of blood in the discrete blotches of blood on the blotter paper during the BT test and thus the BVT gleans valuable additional information from the bleeding time test (BTT)procedure. We hypothesize that the BV test will be a more accurate, specific and sensitive test for diagnosing platelet function abnormalities and for detecting a person's bleeding tendency compared to the BTT, and commercially available in-vitro platelet function tests.

Key facts

Study ID

NCT01047722

Run by

Klein, Jeffrey A., M.D.

People needed

100

Starts

2010-01-01

Expected to finish

2015-10-01

Last updated by the study team

2015-07-21

Who can join

Age: 18 and older, up to 89. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Adult male and female
• Ages 18 to 89 years old

You may not qualify if…

• Any history of HIV, Hepatitis C or presence of a blood-borne infectious disease

Where it is running

• Private practice office — Newport Beach, California, United States
• Capistrano Surgery Center — San Juan Capistrano, California, United States

Full record on ClinicalTrials.gov

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