Study for the Liquid Chromatography-mass Spectrometry (LC-MS/MS) Assessment of Oxidative DNA Damage in Relation to Antioxidant Usage
Completed · Not applicable
Conditions studied: Cancer
In brief
The purpose of this study is to evaluate the basis for the reported good effects of antioxidant supplementation. A blood test using Mass Spectrometry will measure DNA damage which is expected to decrease with antioxidant administration and therefore decrease the risk of cancer.
Key facts
- Study ID
- NCT01038024
- Run by
- Roswell Park Cancer Institute
- People needed
- 38
- Starts
- 2010-01-01
- Expected to finish
- 2012-07-01
- Last updated by the study team
- 2013-03-08
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Health male or female non-melanoma patients or volunteers
- 18 years or older with a life expectancy greater than 6 months
- Willing to provide pre and post blood samples to measure five DNA modifications in white blood cells
- Willing to participate in a one tablet a day eight week supplement program and to record the ingestion of the supplement on a participant calendar
- Must have never smoked or has not smoked for at least 6 months
- Informed of the investigational nature of the study, is able to provide informed consent and has signed thee informed consent form
You may not qualify if…
- Patients/healthy volunteers not meeting all of the above selection criteria.
- Patients/healthy volunteers who have a history of kidney stones within the last 5 years.
- Any participant with life threatening conditions including but not limited to cardiac failure, congestive heart failure, unstable coronary artery disease, uncontrolled hypertension, poorly controlled diabetes mellitus, kidney and liver disease,severe metabolic disorders and advanced cancer
- Patients not willing to comply with protocol requirements
Where it is running
- Roswell Park Cancer Institute — Buffalo, New York, United States
Full record on ClinicalTrials.gov
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